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Beitragstitel Formation of unusual prenyl pyrophosphates by (SAM)-dependent methyltransferases
Beitragscode P40
  1. Parab Jainal Haque DECHEMA-Forschungsinstitut Präsentierende:r
  2. Markus Buchhaupt DECHEMA-Forschungsinstitut
  3. Jens Schrader DECHEMA-Forschungsinstitut
Präsentationsform Poster
  • Posterbeitrag/ Poster Lecture
Abstract-Datei Abstract-Datei ansehen
Abstract-Text Terpenoids represent the largest and most diverse class of natural products with more than 80.000 compounds.1 Although the terpene biosynthesis pathways are highly modular and lead to immense structural diversity, their universal terpene building blocks are almost exclusively the C5 units IPP (isopentenyl pyrophosphate) and DMAPP (dimethylallyl pyrophosphate). The structural diversity of terpenoids and thereby the biotechnological exploitation of terpenoid biosynthesis would be greatly expanded if modifications could be added to the canonical building blocks. Such a strategy would take advantage of the generally high substrate promiscuity of prenyltransferases and terpene synthases.